Note
These publications were found using a combination of automated Google Scholar searches and manual review. When possible, we show specific identifiers, such as NHCDR cell line IDs, that were cited in the text. In some cases, when no specific identifiers were found, we instead show NHCDR-related terms. The terms are sometimes provided in the form of Google Scholar queries that yield the publication, such "repository" "ninds" "ipsc" OR "fibroblast" (you can try this search here). If you have access to the full text of the publication (we provide links when possible), you can search the text for the IDs and/or terms to determine exactly how NHCDR resources were used in the publication.
We are grateful to SerpApi for providing critical data mining services used to produce this list.
This collection was formerly maintained at the Coriell Repository. While some papers may still reference Coriell, the cell line resources they used are now maintained at the NHCDR.
2021
1. Al-Ahmad AJ, …, Karamyan VT. Neurolysin substrates bradykinin, neurotensin and substance P enhance brain microvascular permeability in a human in vitro model. J Neuroendocrinol (2021 Feb)
[PubMed 33506602] [PMC Free Text] [DOI 10.1111/jne.12931] [Related Cell Line IDs: ND41865]
2. Cai J, …, Iacovitti L. A stress-free strategy to correct point mutations in patient iPS cells. Stem Cell Res (2021 May)
[PubMed 33857832] [PMC Free Text] [DOI 10.1016/j.scr.2021.102332] [Related Cell Line IDs: ND40018]
3. Ciesiolka A, …, Fiszer A. Artificial miRNAs targeting CAG repeat expansion in ORFs cause rapid deadenylation and translation inhibition of mutant transcripts. Cell Mol Life Sci (2021 Feb)
[PubMed 32696070] [PMC Free Text] [DOI 10.1007/s00018-020-03596-7] [Related Cell Line IDs: ND42222]
4. Ding B, …, Zhang CL. Disease Modeling with Human Neurons Reveals LMNB1 Dysregulation Underlying DYT1 Dystonia. J Neurosci (2021 Mar 3)
[PubMed 33468570] [PMC Free Text] [DOI 10.1523/JNEUROSCI.2507-20.2020] [Related Subject IDs: NDS00301, NDS00305]
5. Drabik K, …, Szczepanowska J. Effect of Chronic Stress Present in Fibroblasts Derived from Patients with a Sporadic Form of AD on Mitochondrial Function and Mitochondrial Turnover. Antioxidants (Basel) (2021 Jun 10)
[PubMed 34200581] [PMC Free Text] [DOI 10.3390/antiox10060938] [Related Cell Line IDs: ND34769, ND36091, ND36320]
6. Fukusumi H, …, Kanemura Y. Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson’s disease patient (PARK4) with SNCA triplication. FEBS Open Bio (2021 Feb)
[PubMed 33301617] [PMC Free Text] [DOI 10.1002/2211-5463.13060] [Related Cell Line IDs: ND27760]
7. Gaweda-Walerych K, …, Zekanowski C. Parkin Levels Decrease in Fibroblasts With Progranulin (PGRN) Pathogenic Variants and in a Cellular Model of PGRN Deficiency. Front Mol Neurosci (2021)
[PubMed 34054428] [PMC Free Text] [DOI 10.3389/fnmol.2021.676478] [Related Cell Line IDs: ND40082, ND42493]
8. Jo J, …, Je HS. Lewy Body-like Inclusions in Human Midbrain Organoids Carrying Glucocerebrosidase and α-Synuclein Mutations. Ann Neurol (2021 Jul 20)
[PubMed 34288055] [DOI 10.1002/ana.26166] [Related Cell Line IDs: ND34391]
9. Kerschner JL, …, Harris A. OTX2 regulates CFTR expression during endoderm differentiation and occupies 3′ cis-regulatory elements. Dev Dyn (2021 May)
[PubMed 33386644] [DOI 10.1002/dvdy.293] [Related RUIDs: CR0000008]
10. Killoy KM, …, Vargas MR. Altered expression of clock and clock-controlled genes in a hSOD1-linked amyotrophic lateral sclerosis mouse model. FASEB J (2021 Feb)
[PubMed 33508151] [PMC Free Text] [DOI 10.1096/fj.202000386RR] [Related Cell Line IDs: ND38555, ND39034, ND39036] [Related RUIDs: FA0000010]
11. Kim H, …, Seol W. Ciliogenesis is Not Directly Regulated by LRRK2 Kinase Activity in Neurons. Exp Neurobiol (2021 Jun 30)
[PubMed 34230223] [PMC Free Text] [DOI 10.5607/en21003] [Related Cell Line IDs: ND38262]
12. Liu Y, …, Brown RH Jr. Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models. Nat Commun (2021 Feb 8)
[PubMed 33558503] [PMC Free Text] [DOI 10.1038/s41467-021-21112-8] [Related Cell Line IDs: ND50000] [Related External Line IDs: TALS9-9.3 (for ND50000) (Target ALS ID)]
13. Lynch EM, …, Suzuki M. Transcriptome analysis using patient iPSC-derived skeletal myocytes: Bet1L as a new molecule possibly linked to neuromuscular junction degeneration in ALS. Exp Neurol (2021 Jul 24)
[PubMed 34310943] [DOI 10.1016/j.expneurol.2021.113815] [Related Subject IDs: NDS00239, NDS00243, NDS00244, NDS00245, NDS00248]
14. Mathieu C, …, Porotto M. Molecular Features of the Measles Virus Viral Fusion Complex That Favor Infection and Spread in the Brain. mBio (2021 Jun 29)
[PubMed 34061592] [PMC Free Text] [DOI 10.1128/mBio.00799-21] [Related RUIDs: FA0000010, FA0000011]
15. McAlpine CS, …, Swirski FK. Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease. Nature (2021 Jul)
[PubMed 34262178] [DOI 10.1038/s41586-021-03734-6] [Related Subject IDs: NDS00159]
16. Otake K, …, Iwata H. Quantitative comparison of the mRNA content of human iPSC-derived motor neurons and their extracellular vesicles. FEBS Open Bio (2021 Feb)
[PubMed 33296136] [PMC Free Text] [DOI 10.1002/2211-5463.13059] [Related Cell Line IDs: ND50007]
17. Paul S, …, Pulst SM. Staufen1 in Human Neurodegeneration. Ann Neurol (2021 Jun)
[PubMed 33745139] [DOI 10.1002/ana.26069] [Related Cell Line IDs: ND29510, ND31038, ND32947, ND33392, ND34730, ND34732, ND34769, ND38530, ND40069, ND40074, ND40536, ND41001, ND41003, ND42504, ND42506]
18. Pereira JD, …, Wainger BJ. Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form neuromuscular junctions. Nat Commun (2021 Aug 6)
[PubMed 34362895] [DOI 10.1038/s41467-021-24776-4] [Related RUIDs: FA0000011, FA0000012]
19. Ramírez-Nuñez O, …, Portero-Otin M. Nuclear lipidome is altered in amyotrophic lateral sclerosis: A pilot study. J Neurochem (2021 Jul)
[PubMed 33905537] [DOI 10.1111/jnc.15373] [Related Cell Line IDs: ND35663, ND41865, ND42765]
20. Ramos-Gonzalez P, …, Cavaliere F. Astrocytic atrophy as a pathological feature of Parkinson’s disease with LRRK2 mutation. NPJ Parkinsons Dis (2021 Mar 30)
[PubMed 33785762] [PMC Free Text] [DOI 10.1038/s41531-021-00175-w] [Related Google Scholar Queries: "coriell" "ninds" "ipsc" OR "fibroblast", "repository" "ninds" "ipsc" OR "fibroblast"]
21. Simkin D, …, Kiskinis E. Dyshomeostatic modulation of Ca2+-activated K+ channels in a human neuronal model of KCNQ2 encephalopathy. Elife (2021 Feb 5)
[PubMed 33544076] [PMC Free Text] [DOI 10.7554/eLife.64434] [Related Cell Line IDs: ND50031]
22. Simone R, …, de Silva R. MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration. Nature (2021 Jun)
[PubMed 34012113] [PMC Free Text] [DOI 10.1038/s41586-021-03556-6] [Related Cell Line IDs: ND41866]
23. Stabley DL, …, Butchbach MER. Detection of SMN1 to SMN2 gene conversion events and partial SMN1 gene deletions using array digital PCR. Neurogenetics (2021 Mar)
[PubMed 33415588] [DOI 10.1007/s10048-020-00630-5] [Related Cell Line IDs: ND29563, ND32947, ND39027, ND40077, ND41003]
24. Stelcer E, …, Suchorska WM. Ionizing radiation exposure of stem cell-derived chondrocytes affects their gene and microRNA expression profiles and cytokine production. Sci Rep (2021 Apr 5)
[PubMed 33820914] [PMC Free Text] [DOI 10.1038/s41598-021-86230-1] [Related Cell Line IDs: ND41658]
25. Virlogeux A, …, Saudou F. Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice. Sci Adv (2021 Mar)
[PubMed 33789888] [PMC Free Text] [DOI 10.1126/sciadv.abb0799] [Related Cell Line IDs: ND42222]
26. Williams E, …, Bullock AN. Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva. JCI Insight (2021 Apr 22)
[PubMed 33705358] [PMC Free Text] [DOI 10.1172/jci.insight.95042] [Related Cell Line IDs: ND34770]
2020
27. Badu-Mensah A, …, Hickman JJ. Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression. Sci Rep (2020 Aug 31)
[PubMed 32868812] [PMC Free Text] [DOI 10.1038/s41598-020-70510-3] [Related Cell Line IDs: ND35662, ND39032, ND41865]
28. Candelario KM, …, Steindler DA. Exosome/microvesicle content is altered in leucine-rich repeat kinase 2 mutant induced pluripotent stem cell-derived neural cells. J Comp Neurol (2020 May)
[PubMed 31743443] [DOI 10.1002/cne.24819] [Related Cell Line IDs: ND40018, ND40019, ND41865]
29. Chen V, …, Chiba-Falek O. The mechanistic role of alpha-synuclein in the nucleus: impaired nuclear function caused by familial Parkinson’s disease SNCA mutations. Hum Mol Genet (2020 Nov 4)
[PubMed 32954426] [PMC Free Text] [DOI 10.1093/hmg/ddaa183] [Related Cell Line IDs: ND34391, ND50050, ND50085]
30. Chlebowski AC, …, Kisby GE. Protocol for High-Throughput Screening of Neural Cell or Brain Tissue Protein Using a Dot-Blot Technique with Near-Infrared Imaging. STAR Protoc (2020 Sep 18)
[PubMed 33043308] [PMC Free Text] [DOI 10.1016/j.xpro.2020.100054] [Related Cell Line IDs: ND50031]
31. Colón A, …, Hickman JJ. Differentiation of Intrafusal Fibers from Human Induced Pluripotent Stem Cells. ACS Chem Neurosci (2020 Apr 1)
[PubMed 32159941] [DOI 10.1021/acschemneuro.0c00055] [Related Cell Line IDs: ND41865]
32. Dabrowska M, …, Olejniczak M. Generation of New Isogenic Models of Huntington’s Disease Using CRISPR-Cas9 Technology. Int J Mol Sci (2020 Mar 8)
[PubMed 32182692] [PMC Free Text] [DOI 10.3390/ijms21051854] [Related Cell Line IDs: ND42222]
33. Das Sharma S, …, Wyllie DJA. Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns. Mol Autism (2020 Jun 19)
[PubMed 32560741] [PMC Free Text] [DOI 10.1186/s13229-020-00351-4] [Related Cell Line IDs: ND30625]
34. Depla JA, …, Evers MM. Cerebral Organoids: A Human Model for AAV Capsid Selection and Therapeutic Transgene Efficacy in the Brain. Mol Ther Methods Clin Dev (2020 Sep 11)
[PubMed 32637448] [PMC Free Text] [DOI 10.1016/j.omtm.2020.05.028] [Related Cell Line IDs: ND42229]
35. Dhingra A, …, Heutink P. Automated Production of Human Induced Pluripotent Stem Cell-Derived Cortical and Dopaminergic Neurons with Integrated Live-Cell Monitoring. J Vis Exp (2020 Aug 6)
[PubMed 32831313] [DOI 10.3791/61525] [Related Cell Line IDs: ND41865]
36. Di Marco A, …, Muñoz-Sanjuán I. Establishment of an in Vitro Human Blood-Brain Barrier Model Derived from Induced Pluripotent Stem Cells and Comparison to a Porcine Cell-Based System. Cells (2020 Apr 16)
[PubMed 32316221] [PMC Free Text] [DOI 10.3390/cells9040994] [Related RUIDs: NN0004300]
37. Fox LM, …, Yamamoto A. Huntington’s Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy. Neuron (2020 Mar 4)
[PubMed 31899071] [PMC Free Text] [DOI 10.1016/j.neuron.2019.12.003] [Related Cell Line IDs: ND33947]
38. Franco A, …, Dorn GW 2nd. Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A. Elife (2020 Oct 19)
[PubMed 33074106] [PMC Free Text] [DOI 10.7554/eLife.61119] [Related Cell Line IDs: ND29178, ND29510, ND34769, ND34770, ND36320, ND38530]
39. Garcia-Diaz A, …, Wichterle H. Standardized Reporter Systems for Purification and Imaging of Human Pluripotent Stem Cell-derived Motor Neurons and Other Cholinergic Cells. Neuroscience (2020 Dec 1)
[PubMed 32615233] [PMC Free Text] [DOI 10.1016/j.neuroscience.2020.06.028] [Related Cell Line IDs: ND50004, NH50162, NH50164, NH50275, NH50285, NH50286] [Related External Line IDs: NCRM-1 (for ND50028) (RMP Cell Line ID), TALSCTRL15.12 (for ND50004) (Target ALS ID)]
40. García-León JA, …, Verfaillie CM. Generation of oligodendrocytes and establishment of an all-human myelinating platform from human pluripotent stem cells. Nat Protoc (2020 Nov)
[PubMed 33097924] [DOI 10.1038/s41596-020-0395-4] [Related Cell Line IDs: ND35671]
41. Guo X, …, Hickman JJ. Characterization of Functional Human Skeletal Myotubes and Neuromuscular Junction Derived-From the Same Induced Pluripotent Stem Cell Source. Bioengineering (Basel) (2020 Oct 22)
[PubMed 33105732] [PMC Free Text] [DOI 10.3390/bioengineering7040133] [Related Cell Line IDs: ND41865]
42. Guo X, …, Hickman JJ. A Human-Based Functional NMJ System for Personalized ALS Modeling and Drug Testing. Adv Ther (Weinh) (2020 Nov)
[PubMed 33709015] [PMC Free Text] [DOI 10.1002/adtp.202000133] [Related Cell Line IDs: ND35660, ND39032, ND39034, ND41865]
43. Huang H, …, Jin S. Signaling Molecules Regulating Pancreatic Endocrine Development from Pluripotent Stem Cell Differentiation. Int J Mol Sci (2020 Aug 15)
[PubMed 32824212] [PMC Free Text] [DOI 10.3390/ijms21165867] [Related Cell Line IDs: ND41866]
44. Kerschner JL, …, Harris A. A functional genomics approach to investigate the differentiation of iPSCs into lung epithelium at air-liquid interface. J Cell Mol Med (2020 Sep)
[PubMed 32692488] [PMC Free Text] [DOI 10.1111/jcmm.15568] [Related RUIDs: CR0000008, CR0000011]
45. Korecka JA, …, Hastings ML. Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice. Mol Ther Nucleic Acids (2020 Sep 4)
[PubMed 32736291] [PMC Free Text] [DOI 10.1016/j.omtn.2020.06.027] [Related Cell Line IDs: ND35367]
46. Lee JE, …, Kim J. Neuroprotective Effects of Cryptotanshinone in a Direct Reprogramming Model of Parkinson’s Disease. Molecules (2020 Aug 7)
[PubMed 32784741] [PMC Free Text] [DOI 10.3390/molecules25163602] [Related Cell Line IDs: ND38262]
47. Li S, …, Lu B. Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD. Cell Rep (2020 Aug 4)
[PubMed 32755582] [PMC Free Text] [DOI 10.1016/j.celrep.2020.107989] [Related Cell Line IDs: ND29510, ND29971]
48. Mannhardt I, …, Eschenhagen T. Comparison of 10 Control hPSC Lines for Drug Screening in an Engineered Heart Tissue Format. Stem Cell Reports (2020 Oct 13)
[PubMed 33053362] [PMC Free Text] [DOI 10.1016/j.stemcr.2020.09.002] [Related Cell Line IDs: ND50031]
49. Ortega JA, …, Kiskinis E. Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity. Neuron (2020 Apr 8)
[PubMed 32059759] [PMC Free Text] [DOI 10.1016/j.neuron.2020.01.020] [Related Cell Line IDs: ND50000, ND50001, ND50004, ND50008]
50. Patel A, …, Hickman JJ. Myelination and Node of Ranvier Formation in a Human Motoneuron-Schwann Cell Serum-Free Coculture. ACS Chem Neurosci (2020 Sep 2)
[PubMed 32786317] [DOI 10.1021/acschemneuro.0c00287] [Related Cell Line IDs: ND41865]
51. Patel A, …, Corneo B. Establishment and characterization of two iPSC lines derived from healthy controls. Stem Cell Res (2020 Jul 25)
[PubMed 32738631] [DOI 10.1016/j.scr.2020.101926] [Related RUIDs: FA0000010, FA0000011]
52. Schwartzentruber A, …, Mortiboys H. Oxidative switch drives mitophagy defects in dopaminergic parkin mutant patient neurons. Sci Rep (2020 Sep 23)
[PubMed 32968089] [PMC Free Text] [DOI 10.1038/s41598-020-72345-4] [Related Cell Line IDs: ND29510, ND30171, ND31618, ND40067, ND40078]
53. Semmler S, …, Vande Velde C. TNF receptor-associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation. J Biol Chem (2020 Mar 20)
[PubMed 32029478] [PMC Free Text] [DOI 10.1074/jbc.RA119.011215]
54. Sim H, …, Kim J. Iroquois Homeobox Protein 2 Identified as a Potential Biomarker for Parkinson’s Disease. Int J Mol Sci (2020 May 14)
[PubMed 32422864] [PMC Free Text] [DOI 10.3390/ijms21103455] [Related Cell Line IDs: ND29492, ND33879, ND38262]
55. Sim H, …, Kim J. Quantitative Proteomic Analysis of Primitive Neural Stem Cells from LRRK2 G2019S-Associated Parkinson’s Disease Patient-Derived iPSCs. Life (Basel) (2020 Dec 7)
[PubMed 33297425] [PMC Free Text] [DOI 10.3390/life10120331] [Related Cell Line IDs: ND38262]
56. Svrzikapa N, …, Goyal J. Investigational Assay for Haplotype Phasing of the Huntingtin Gene. Mol Ther Methods Clin Dev (2020 Dec 11)
[PubMed 33209959] [PMC Free Text] [DOI 10.1016/j.omtm.2020.09.003] [Related Cell Line IDs: ND30259]
57. Thelin EP, …, Helmy A. Delineating Astrocytic Cytokine Responses in a Human Stem Cell Model of Neural Trauma. J Neurotrauma (2020 Jan 1)
[PubMed 31452443] [PMC Free Text] [DOI 10.1089/neu.2019.6480] [Related Cell Line IDs: ND41866]
58. Thiruvalluvan A, …, Kampinga HH. DNAJB6, a Key Factor in Neuronal Sensitivity to Amyloidogenesis. Mol Cell (2020 Apr 16)
[PubMed 32268123] [DOI 10.1016/j.molcel.2020.02.022] [Related Cell Line IDs: ND36997, ND36999, ND41656, ND42230, ND42242]
59. Tran RDH, …, Grosberg A. The Effect of Cyclic Strain on Human Fibroblasts With Lamin A/C Mutations and Its Relation to Heart Disease. J Biomech Eng (2020 Jun 1)
[PubMed 31233093] [PMC Free Text] [DOI 10.1115/1.4044091] [Related Cell Line IDs: ND31845]
60. Vázquez-Vélez GE, …, Zoghbi HY. Doublecortin-like Kinase 1 Regulates α-Synuclein Levels and Toxicity. J Neurosci (2020 Jan 8)
[PubMed 31748376] [PMC Free Text] [DOI 10.1523/JNEUROSCI.1076-19.2019] [Related Cell Line IDs: ND34391, ND50040, ND50042] [Related RUIDs: NN0000049, NN0003871] [Related Subject IDs: NDS00201]
61. Voisin J, …, Neri C. FOXO3 targets are reprogrammed as Huntington’s disease neural cells and striatal neurons face senescence with p16INK4a increase. Aging Cell (2020 Nov)
[PubMed 33156570] [PMC Free Text] [DOI 10.1111/acel.13226] [Related Cell Line IDs: ND41656, ND42222, ND42241]
62. White JA 2nd, …, Gunawardena S. Excess Rab4 rescues synaptic and behavioral dysfunction caused by defective HTT-Rab4 axonal transport in Huntington’s disease. Acta Neuropathol Commun (2020 Jul 1)
[PubMed 32611447] [PMC Free Text] [DOI 10.1186/s40478-020-00964-z] [Related Cell Line IDs: ND38555, ND42222]
63. Widyastuti HP, …, Zaragoza MV. Gene expression profiling of fibroblasts in a family with LMNA-related cardiomyopathy reveals molecular pathways implicated in disease pathogenesis. BMC Med Genet (2020 Jul 22)
[PubMed 32698886] [PMC Free Text] [DOI 10.1186/s12881-020-01088-w] [Related Cell Line IDs: ND31845]
64. Xu X, …, Pouladi MA. pS421 huntingtin modulates mitochondrial phenotypes and confers neuroprotection in an HD hiPSC model. Cell Death Dis (2020 Sep 25)
[PubMed 32978366] [PMC Free Text] [DOI 10.1038/s41419-020-02983-z] [Related Cell Line IDs: ND36997, ND36999]
65. Zhang W, …, Chen JF. Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes. Genes Dev (2020 Apr 1)
[PubMed 32115408] [PMC Free Text] [DOI 10.1101/gad.332494.119] [Related RUIDs: CR0000010]
2019
66. Abdul MM, …, Luo Z. Generation of an induced pluripotent stem cell line (GIBHi003-A) from a Parkinson’s disease patient with mutant PINK1 (p. I368N). Stem Cell Res (2019 Dec)
[PubMed 31778937] [DOI 10.1016/j.scr.2019.101607] [Related Cell Line IDs: ND40066]
67. Aviolat H, …, DiFiglia M. Assessing average somatic CAG repeat instability at the protein level. Sci Rep (2019 Dec 16)
[PubMed 31844074] [PMC Free Text] [DOI 10.1038/s41598-019-55202-x] [Related Cell Line IDs: ND38551]
68. Babos KN, …, Ichida JK. Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming. Cell Stem Cell (2019 Oct 3)
[PubMed 31523028] [PMC Free Text] [DOI 10.1016/j.stem.2019.08.005] [Related Cell Line IDs: ND39023]
69. Blackford SJI, …, Rashid ST. Validation of Current Good Manufacturing Practice Compliant Human Pluripotent Stem Cell-Derived Hepatocytes for Cell-Based Therapy. Stem Cells Transl Med (2019 Feb)
[PubMed 30456803] [PMC Free Text] [DOI 10.1002/sctm.18-0084] [Related Cell Line IDs: NH50191] [Note: while not referenced in the text, we are aware that cell line NH50191 was used in this work.]
70. Bredenkamp N, …, Guo G. The Cell-Surface Marker Sushi Containing Domain 2 Facilitates Establishment of Human Naive Pluripotent Stem Cells. Stem Cell Reports (2019 Jun 11)
[PubMed 31031191] [PMC Free Text] [DOI 10.1016/j.stemcr.2019.03.014] [Related External Line IDs: NCRM-2 (for ND50030) (RMP Cell Line ID)]
71. Burbulla LF, …, Krainc D. A modulator of wild-type glucocerebrosidase improves pathogenic phenotypes in dopaminergic neuronal models of Parkinson’s disease. Sci Transl Med (2019 Oct 16)
[PubMed 31619543] [PMC Free Text] [DOI 10.1126/scitranslmed.aau6870] [Related Cell Line IDs: ND39896]
72. Cuddy LK, …, Mazzulli JR. Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein. Neuron (2019 Dec 4)
[PubMed 31648898] [PMC Free Text] [DOI 10.1016/j.neuron.2019.09.001] [Related Cell Line IDs: ND34391]
73. Custer SK, …, Androphy EJ. Abnormal Golgi morphology and decreased COPI function in cells with low levels of SMN. Brain Res (2019 Mar 1)
[PubMed 30408476] [PMC Free Text] [DOI 10.1016/j.brainres.2018.11.005] [Related Cell Line IDs: ND29563]
74. Goodman LD, …, Bonini NM. Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD. Nat Neurosci (2019 Jun)
[PubMed 31110321] [PMC Free Text] [DOI 10.1038/s41593-019-0396-1] [Related Cell Line IDs: ND40069, ND42496, ND42504, ND42506] [Note: lines ND42504, ND42506, ND42496 and ND40069 are referenced in Supplementary Figure 10a]
75. Hsieh CH, …, Wang X. Miro1 Marks Parkinson’s Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson’s Models. Cell Metab (2019 Dec 3)
[PubMed 31564441] [PMC Free Text] [DOI 10.1016/j.cmet.2019.08.023] [Related Cell Line IDs: ND39896, ND41864, ND50050, ND50085]
76. Hu D, …, Qi X. Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity. Acta Neuropathol (2019 Jun)
[PubMed 30877431] [PMC Free Text] [DOI 10.1007/s00401-019-01993-2] [Related RUIDs: NN0004337, NN0004344]
77. Jiang X, …, McMahon FJ. Sodium valproate rescues expression of TRANK1 in iPSC-derived neural cells that carry a genetic variant associated with serious mental illness. Mol Psychiatry (2019 Apr)
[PubMed 30135510] [PMC Free Text] [DOI 10.1038/s41380-018-0207-1] [Related Cell Line IDs: ND50028, ND50031] [Note: Lines ND50028 and ND50031 are referenced as NL1 and NL5, respectively, in supplementary Table S5. These lines are also known as NCRM-1 and NCRM-5, respectively.]
78. Karch CM, …, Temple S. A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies. Stem Cell Reports (2019 Nov 12)
[PubMed 31631020] [PMC Free Text] [DOI 10.1016/j.stemcr.2019.09.006] [Related Google Scholar Queries: "repository" "ninds" "ipsc" OR "fibroblast"]
79. Katt ME, …, Searson PC. The role of mutations associated with familial neurodegenerative disorders on blood-brain barrier function in an iPSC model. Fluids Barriers CNS (2019 Jul 15)
[PubMed 31303172] [PMC Free Text] [DOI 10.1186/s12987-019-0139-4] [Related RUIDs: NN0000049, NN0000052, NN0003930, NN0003949] [Note: these RUIDs appear in the “Source” column of Table 1 in this paper.]
80. Keskin S, …, Evers MM. AAV5-miHTT Lowers Huntingtin mRNA and Protein without Off-Target Effects in Patient-Derived Neuronal Cultures and Astrocytes. Mol Ther Methods Clin Dev (2019 Dec 13)
[PubMed 31737741] [PMC Free Text] [DOI 10.1016/j.omtm.2019.09.010] [Related Cell Line IDs: ND42229, ND42245]
81. Kim J, …, Daadi MM. Non-cell autonomous mechanism of Parkinson’s disease pathology caused by G2019S LRRK2 mutation in Ashkenazi Jewish patient: Single cell analysis. Brain Res (2019 Nov 1)
[PubMed 31330122] [PMC Free Text] [DOI 10.1016/j.brainres.2019.146342] [Related Cell Line IDs: ND29802]
82. Kulcenty K, …, Suchorska WM. MicroRNA Profiling During Neural Differentiation of Induced Pluripotent Stem Cells. Int J Mol Sci (2019 Jul 26)
[PubMed 31357387] [PMC Free Text] [DOI 10.3390/ijms20153651] [Related Cell Line IDs: ND41658]
83. Lee M, …, Kim J. Direct Reprogramming to Human Induced Neuronal Progenitors from Fibroblasts of Familial and Sporadic Parkinson’s Disease Patients. Int J Stem Cells (2019 Nov 30)
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84. Li H, …, Tang G. Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations. Autophagy (2019 Jan)
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85. Lynch E, …, Suzuki M. C9ORF72-related cellular pathology in skeletal myocytes derived from ALS-patient induced pluripotent stem cells. Dis Model Mech (2019 Aug 16)
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86. Martier R, …, Konstantinova P. Targeting RNA-Mediated Toxicity in C9orf72 ALS and/or FTD by RNAi-Based Gene Therapy. Mol Ther Nucleic Acids (2019 Jun 7)
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87. Martier R, …, Konstantinova P. Artificial MicroRNAs Targeting C9orf72 Can Reduce Accumulation of Intra-nuclear Transcripts in ALS and FTD Patients. Mol Ther Nucleic Acids (2019 Mar 1)
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88. Martier R, …, Evers MM. Development of an AAV-Based MicroRNA Gene Therapy to Treat Machado-Joseph Disease. Mol Ther Methods Clin Dev (2019 Dec 13)
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89. Ouchi R, …, Takebe T. Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids. Cell Metab (2019 Aug 6)
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90. Page S, …, Al-Ahmad A. Oxygen-Glucose Deprivation/Reoxygenation-Induced Barrier Disruption at the Human Blood-Brain Barrier is Partially Mediated Through the HIF-1 Pathway. Neuromolecular Med (2019 Dec)
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91. Ren C, …, Liu CF. A compendious summary of Parkinson’s disease patient-derived iPSCs in the first decade. Ann Transl Med (2019 Nov)
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92. Sarraf SA, …, Pickrell AM. PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. Cell Rep (2019 Oct 1)
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93. Tagliafierro L, …, Chiba-Falek O. Multiplication of the SNCA locus exacerbates neuronal nuclear aging. Hum Mol Genet (2019 Feb 1)
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94. Tagliafierro L, …, Kantor B. Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models. J Vis Exp (2019 Mar 29)
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95. Tousley A, …, Kegel-Gleason KB. Rac1 Activity Is Modulated by Huntingtin and Dysregulated in Models of Huntington’s Disease. J Huntingtons Dis (2019)
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96. Vethe H, …, Ræder H. The Effect of Wnt Pathway Modulators on Human iPSC-Derived Pancreatic Beta Cell Maturation. Front Endocrinol (Lausanne) (2019)
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97. Xue Y, …, Ying M. Synthetic mRNAs Drive Highly Efficient iPS Cell Differentiation to Dopaminergic Neurons. Stem Cells Transl Med (2019 Feb)
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98. Yamada SB, …, Gitler AD. RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats. Nat Neurosci (2019 Sep)
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99. Zeitler B, …, Zhang HS. Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease. Nat Med (2019 Jul)
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100. Zhang W, …, Chen JF. Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors. Nat Commun (2019 Jun 13)
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2018
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103. Bell SM, …, Mortiboys H. Ursodeoxycholic Acid Improves Mitochondrial Function and Redistributes Drp1 in Fibroblasts from Patients with Either Sporadic or Familial Alzheimer’s Disease. J Mol Biol (2018 Oct 19)
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104. Bowie LE, …, Truant R. N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation. Proc Natl Acad Sci U S A (2018 Jul 24)
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105. Cantley W, …, Kaplan DL. Functional and Sustainable 3D Human Neural Network Models from Pluripotent Stem Cells. ACS Biomater Sci Eng (2018 Dec 10)
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107. Fog CK, …, Kirkegaard T. The heat shock protein amplifier arimoclomol improves refolding, maturation and lysosomal activity of glucocerebrosidase. EBioMedicine (2018 Dec)
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108. Fontaine KA, …, Ott M. The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein. mBio (2018 Nov 6)
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109. Ho DH, …, Seol W. LRRK2 impairs autophagy by mediating phosphorylation of leucyl-tRNA synthetase. Cell Biochem Funct (2018 Dec)
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110. Hung CL, …, Truant R. A patient-derived cellular model for Huntington’s disease reveals phenotypes at clinically relevant CAG lengths. Mol Biol Cell (2018 Nov 15)
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111. Irmak D, …, Vilchez D. Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations. Hum Mol Genet (2018 Dec 1)
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112. Je G, …, Kim YS. A novel extended form of alpha-synuclein 3’UTR in the human brain. Mol Brain (2018 May 25)
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113. Joshi AU, …, Mochly-Rosen D. Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis. EMBO Mol Med (2018 Mar)
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114. Kantor B, …, Chiba-Falek O. Downregulation of SNCA Expression by Targeted Editing of DNA Methylation: A Potential Strategy for Precision Therapy in PD. Mol Ther (2018 Nov 7)
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115. Kelley KW, …, Rowitch DH. Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength. Neuron (2018 Apr 18)
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116. Koyuncu S, …, Vilchez D. The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington’s disease patients. Nat Commun (2018 Jul 23)
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117. Luisier R, …, Patani R. Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS. Nat Commun (2018 May 22)
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118. Ma G, …, Mccright B. Evaluation of the differentiation status of neural stem cells based on cell morphology and the expression of Notch and Sox2. Cytotherapy (2018 Dec)
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119. Mahadevan A, …, . Network Analysis of Developing Neural Progenitor Cells. (2018 Aug 1)
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120. McCoy MJ, …, Ahn TH. LONGO: an R package for interactive gene length dependent analysis for neuronal identity. Bioinformatics (2018 Jul 1)
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121. McGowan H, …, Pang ZP. hsa-let-7c miRNA Regulates Synaptic and Neuronal Function in Human Neurons. Front Synaptic Neurosci (2018)
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122. Milanese C, …, Mastroberardino PG. Mitochondrial Complex I Reversible S-Nitrosation Improves Bioenergetics and Is Protective in Parkinson’s Disease. Antioxid Redox Signal (2018 Jan 1)
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123. Mueller KA, …, Sadri-Vakili G. Hippo Signaling Pathway Dysregulation in Human Huntington’s Disease Brain and Neuronal Stem Cells. Sci Rep (2018 Jul 27)
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124. Nguyen M, …, Krainc D. LRRK2 phosphorylation of auxilin mediates synaptic defects in dopaminergic neurons from patients with Parkinson’s disease. Proc Natl Acad Sci U S A (2018 May 22)
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125. Osborn TM, …, Isacson O. Increased motor neuron resilience by small molecule compounds that regulate IGF-II expression. Neurobiol Dis (2018 Feb)
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126. Paul S, …, Pulst SM. Staufen1 links RNA stress granules and autophagy in a model of neurodegeneration. Nat Commun (2018 Sep 7)
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127. Pavoni S, …, Yates F. Small-molecule induction of Aβ-42 peptide production in human cerebral organoids to model Alzheimer’s disease associated phenotypes. PLoS One (2018)
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128. Pinarbasi ES, …, Thomas PJ. Pathogenic Signal Sequence Mutations in Progranulin Disrupt SRP Interactions Required for mRNA Stability. Cell Rep (2018 Jun 5)
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129. Romano G, …, Feiguin F. Downregulation of glutamic acid decarboxylase in Drosophila TDP-43-null brains provokes paralysis by affecting the organization of the neuromuscular synapses. Sci Rep (2018 Jan 29)
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131. Stelcer E, …, Suchorska WM. Chondrocytes differentiated from human induced pluripotent stem cells: Response to ionizing radiation. PLoS One (2018)
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132. Świtońska K, …, Figiel M. Identification of Altered Developmental Pathways in Human Juvenile HD iPSC With 71Q and 109Q Using Transcriptome Profiling. Front Cell Neurosci (2018)
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133. Teng YD, …, Zafonte RD. Updates on Human Neural Stem Cells: From Generation, Maintenance, and Differentiation to Applications in Spinal Cord Injury Research. Results Probl Cell Differ (2018)
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134. Victor MB, …, Yoo AS. Striatal neurons directly converted from Huntington’s disease patient fibroblasts recapitulate age-associated disease phenotypes. Nat Neurosci (2018 Mar)
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135. Zou L, …, Zhan X. The Effects of Quinine on Neurophysiological Properties of Dopaminergic Neurons. Neurotox Res (2018 Jul)
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136. Zunke F, …, Mazzulli JR. Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide. Neuron (2018 Jan 3)
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2017
137. Abernathy DG, …, Yoo AS. MicroRNAs Induce a Permissive Chromatin Environment that Enables Neuronal Subtype-Specific Reprogramming of Adult Human Fibroblasts. Cell Stem Cell (2017 Sep 7)
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138. Al-Ahmad AJ, …, Al-Ahmad AJ. Comparative study of expression and activity of glucose transporters between stem cell-derived brain microvascular endothelial cells and hCMEC/D3 cells. Am J Physiol Cell Physiol (2017 Oct 1)
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139. Ando M, …, Springer W. The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity. Mol Neurodegener (2017 Apr 24)
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140. Bhinge A, …, Stanton LW. Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis. Stem Cell Reports (2017 Apr 11)
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141. Chao MJ, …, Lee JM. Haplotype-based stratification of Huntington’s disease. Eur J Hum Genet (2017 Nov)
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142. Chen MZ, …, Hatters DM. A thiol probe for measuring unfolded protein load and proteostasis in cells. Nat Commun (2017 Sep 7)
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143. Core JQ, …, Grosberg A. Age of heart disease presentation and dysmorphic nuclei in patients with LMNA mutations. PLoS One (2017)
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144. Donlin-Asp PG, …, Rossoll W. The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP Assembly. Cell Rep (2017 Feb 14)
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145. Dzamko N, …, Halliday GM. Toll-like receptor 2 is increased in neurons in Parkinson’s disease brain and may contribute to alpha-synuclein pathology. Acta Neuropathol (2017 Feb)
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146. Hall CE, …, Patani R. Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS. Cell Rep (2017 May 30)
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147. Konrad C, …, Manfredi G. Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients. Mol Neurodegener (2017 Oct 24)
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148. Lavado A, …, Hickman JJ. Evaluation of Holistic Treatment for ALS Reveals Possible Mechanism and Therapeutic Potential. Int J Pharm Pharm Res (2017 Dec)
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149. Maiuri T, …, Truant R. Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex. Hum Mol Genet (2017 Jan 15)
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150. Malloy KE, …, Daadi MM. Magnetic Resonance Imaging-Guided Delivery of Neural Stem Cells into the Basal Ganglia of Nonhuman Primates Reveals a Pulsatile Mode of Cell Dispersion. Stem Cells Transl Med (2017 Mar)
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151. Monteys AM, …, Davidson BL. CRISPR/Cas9 Editing of the Mutant Huntingtin Allele In Vitro and In Vivo. Mol Ther (2017 Jan 4)
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152. Oleksiewicz U, …, Wiznerowicz M. TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes. Stem Cell Reports (2017 Dec 12)
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153. Pandya H, …, Park JK. Differentiation of human and murine induced pluripotent stem cells to microglia-like cells. Nat Neurosci (2017 May)
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154. Patel R, …, Al-Ahmad AJ. Isogenic blood-brain barrier models based on patient-derived stem cells display inter-individual differences in cell maturation and functionality. J Neurochem (2017 Jul)
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156. Schwab AJ, …, Ebert AD. Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons. Stem Cell Reports (2017 Dec 12)
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157. Son MY, …, Kim J. Distinctive genomic signature of neural and intestinal organoids from familial Parkinson’s disease patient-derived induced pluripotent stem cells. Neuropathol Appl Neurobiol (2017 Dec)
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158. Szlachcic WJ, …, Figiel M. The Generation of Mouse and Human Huntington Disease iPS Cells Suitable for In vitro Studies on Huntingtin Function. Front Mol Neurosci (2017)
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159. Tagliafierro L, …, Chiba-Falek O. Genetic analysis of α-synuclein 3′ untranslated region and its corresponding microRNAs in relation to Parkinson’s disease compared to dementia with Lewy bodies. Alzheimers Dement (2017 Nov)
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160. Takata K, …, Ginhoux F. Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function. Immunity (2017 Jul 18)
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161. Teves JMY, …, Madhavan L. Parkinson’s Disease Skin Fibroblasts Display Signature Alterations in Growth, Redox Homeostasis, Mitochondrial Function, and Autophagy. Front Neurosci (2017)
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162. Vasquez V, …, Hegde ML. Chromatin-Bound Oxidized α-Synuclein Causes Strand Breaks in Neuronal Genomes in in vitro Models of Parkinson’s Disease. J Alzheimers Dis (2017)
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163. Verma M, …, Chu CT. Mitochondrial Calcium Dysregulation Contributes to Dendrite Degeneration Mediated by PD/LBD-Associated LRRK2 Mutants. J Neurosci (2017 Nov 15)
[PubMed 29038245] [PMC Free Text] [DOI 10.1523/JNEUROSCI.3791-16.2017] [Related Cell Line IDs: ND32975, ND33879, ND34769]
164. Wang L, …, Liu GH. CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs. Protein Cell (2017 May)
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165. Xu X, …, Pouladi MA. Reversal of Phenotypic Abnormalities by CRISPR/Cas9-Mediated Gene Correction in Huntington Disease Patient-Derived Induced Pluripotent Stem Cells. Stem Cell Reports (2017 Mar 14)
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166. Zhong P, …, Feng J. Dopamine Induces Oscillatory Activities in Human Midbrain Neurons with Parkin Mutations. Cell Rep (2017 May 2)
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2016
167. Borgs L, …, Nguyen L. Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Sci Rep (2016 Sep 19)
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168. Cho KJ, …, Hancock JF. Inhibition of Acid Sphingomyelinase Depletes Cellular Phosphatidylserine and Mislocalizes K-Ras from the Plasma Membrane. Mol Cell Biol (2016 Jan 15)
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